Saturday, October 3, 2020

National Geographic: What President Trump’s emergency COVID-19 therapies say about his condition

By Michael Greshko

    President Trump revealed that he had tested positive for COVID-19 on Thursday, and is now undergoing multiple treatments. While he has continually downplayed the severity of his condition, his medical staff and advisors have said that although his condition has improved, the next few days will be critical to his treatment.
    The president is currently on two drugs. One, developed by the US company Regeneron provides monoclonal antibodies, and the other, Remdesevir, has been shown to decrease the recovery duration in patients.
    Monoclonal antibodies are the Y-shaped proteins shown in the picture. They can latch on to the viral body's spike proteins and if enough of them get on it, it can prevent the virus from infecting cells. Regeneron's treatment, called REGN-COV2 is designed to prevent the virus from living in the nose and mouth so that it cannot reach the lungs. The drug is still in the early stages of testing and many medical professionals have been hesitant, using it only on a few special cases.
    The president is also scheduled to have a total of 5 doses of Remdesevir, a repurposed over-the-counter drug that has decreased recovery time in some patients.

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